| # | Verein | Sp | S | D | N | TD | Pkt |
|---|---|---|---|---|---|---|---|
| 1 | Inter Miami CF | 15 | 9 | 5 | 1 | +16 | 32 |
| 2 | FC Cincinnati | 15 | 6 | 6 | 3 | +5 | 24 |
| 3 | Charlotte Football Club | 15 | 7 | 3 | 5 | +3 | 24 |
| 4 | Philadelphia Union | 15 | 5 | 7 | 3 | +3 | 22 |
| 5 | New York Red Bulls | 15 | 5 | 6 | 4 | +3 | 21 |
| 6 | Orlando City | 15 | 5 | 6 | 4 | +2 | 21 |
| 7 | Atlanta United FC | 15 | 5 | 5 | 5 | 0 | 20 |
| 8 | Columbus Crew | 14 | 3 | 10 | 1 | +2 | 19 |
| 9 | Toronto FC | 15 | 5 | 4 | 6 | -1 | 19 |
| 10 | New York City | 15 | 4 | 6 | 5 | 0 | 18 |
| 11 | Nashville SC | 15 | 4 | 6 | 5 | -3 | 18 |
| 12 | CF Montreal | 15 | 4 | 5 | 6 | -4 | 17 |
| 13 | DC United | 15 | 4 | 4 | 7 | -5 | 16 |
| 14 | New England Revolution | 15 | 3 | 4 | 8 | -14 | 13 |
| 15 | Chicago Fire | 15 | 2 | 5 | 8 | -7 | 11 |
| # | Spieler | Spiele | Tore |
|---|---|---|---|
| 1 | Segovia Telasco Inter Miami CF | 15 | 11 |
| 2 | Messi Lionel Inter Miami CF | 15 | 10 |
| 3 | Owusu Prince CF Montreal | 13 | 10 |
| 4 | Griezmann Antoine Orlando City | 15 | 9 |
| 5 | Pirani Gabriel DC United | 14 | 8 |
| 6 | Goodwin Archie Charlotte Football Club | 15 | 8 |
| 7 | Aristizábal Emilio Toronto FC | 14 | 8 |
| 8 | De Asis Jorge New York Red Bulls | 11 | 8 |
| 9 | Allende Tadeo Inter Miami CF | 15 | 7 |
| 10 | Thiago New York City | 14 | 7 |
| # | Spieler | Spiele | Vor |
|---|---|---|---|
| 1 | Panicco Elliot CF Montreal | 15 | 9 |
| 2 | Martínez Alonso New York City | 15 | 8 |
| 3 | Messi Lionel Inter Miami CF | 15 | 6 |
| 4 | Barbi Santino Toronto FC | 12 | 6 |
| 5 | Turner Matt New England Revolution | 15 | 6 |
| 6 | Hoyos Lucas Atlanta United FC | 15 | 5 |
| 7 | Clair Dayne St. Inter Miami CF | 15 | 5 |
| 8 | Pašalić Marco Orlando City | 14 | 5 |
| 9 | Ojeda Martín Orlando City | 15 | 5 |
| 10 | Blake Andre Philadelphia Union | 15 | 5 |
| # | Spieler | Spiele | Bew |
|---|---|---|---|
| 1 | Messi Lionel Inter Miami CF | 15 | 7.67 |
| 2 | Allende Tadeo Inter Miami CF | 15 | 7.45 |
| 3 | Griezmann Antoine Orlando City | 15 | 7.41 |
| 4 | Magno Talles New York City | 15 | 7.38 |
| 5 | Bucha Pavel FC Cincinnati | 15 | 7.36 |
| 6 | Segovia Telasco Inter Miami CF | 15 | 7.35 |
| 7 | Pirani Gabriel DC United | 14 | 7.30 |
| 8 | Méndez Brais Columbus Crew | 14 | 7.27 |
| 9 | Lath Emmanuel Latte Atlanta United FC | 15 | 7.25 |
| 10 | Ojeda Martín Orlando City | 15 | 7.23 |