| Datum | Zeit | Spielort | Gegner | Wettbewerb | Ergebnis |
|---|---|---|---|---|---|
| 12.02.2028 | 00:00 | H | Boston River | Primera Division | 1 - 0 |
| 19.02.2028 | 00:00 | A | Racing | Primera Division | 1 - 2 |
| 26.02.2028 | 00:00 | H | Rentistas | Primera Division | 2 - 1 |
| 04.03.2028 | 00:00 | A | River Plate | Primera Division | 1 - 1 |
| 11.03.2028 | 00:00 | H | Penarol | Primera Division | 1 - 1 |
| 18.03.2028 | 00:00 | A | Liverpool Montevideo | Primera Division | 1 - 1 |
| 25.03.2028 | 00:00 | A | Danubio | Primera Division | 1 - 1 |
| 01.04.2028 | 00:00 | H | Cerro Largo | Primera Division | 3 - 2 |
| 08.04.2028 | 00:00 | A | Miramar Misiones | Primera Division | 0 - 1 |
| 15.04.2028 | 00:00 | H | Juventud | Primera Division | 1 - 0 |
| 22.04.2028 | 00:00 | A | Wanderers | Primera Division | 1 - 0 |
| 29.04.2028 | 00:00 | H | Progreso | Primera Division | 0 - 1 |
| 06.05.2028 | 00:00 | A | Nacional | Primera Division | 2 - 1 |
| 13.05.2028 | 00:00 | H | Cerro | Primera Division | 2 - 1 |
| 20.05.2028 | 00:00 | H | Montevideo City Torque | Primera Division | 2 - 2 |
| 27.05.2028 | 00:00 | A | Boston River | Primera Division | 0 - 1 |
| 03.06.2028 | 00:00 | H | Racing | Primera Division | 2 - 1 |
| 10.06.2028 | 00:00 | A | Rentistas | Primera Division | 1 - 1 |
| 17.06.2028 | 00:00 | H | River Plate | Primera Division | 2 - 0 |
| 24.06.2028 | 00:00 | A | Penarol | Primera Division | 0 - 1 |
| 01.07.2028 | 00:00 | H | Liverpool Montevideo | Primera Division | 1 - 2 |
| 08.07.2028 | 00:00 | H | Danubio | Primera Division | 3 - 2 |
| 15.07.2028 | 00:00 | A | Cerro Largo | Primera Division | 0 - 0 |
| 22.07.2028 | 00:00 | H | Miramar Misiones | Primera Division | 2 - 0 |
| 29.07.2028 | 00:00 | A | Juventud | Primera Division | 0 - 1 |
| 05.08.2028 | 00:00 | H | Wanderers | Primera Division | 1 - 0 |
| 12.08.2028 | 00:00 | A | Progreso | Primera Division | 2 - 2 |
| 19.08.2028 | 00:00 | H | Nacional | Primera Division | 0 - 1 |
| 26.08.2028 | 00:00 | A | Cerro | Primera Division | 1 - 0 |
| 02.09.2028 | 00:00 | A | Montevideo City Torque | Primera Division | 0 - 3 |
| 17.09.2028 | 20:00 | A | Sporting Cristal | Champions League | 2 - 1 |
| 19.09.2028 | 20:00 | H | Talleres | Europa League | 1 - 1 |
| 01.10.2028 | 20:00 | H | Flamengo | Champions League | 2 - 4 |
| 03.10.2028 | 20:00 | H | Sol de America | Europa League | 0 - 2 |
| 22.10.2028 | 20:00 | A | Olimpia | Champions League | 1 - 1 |
| 24.10.2028 | 20:00 | A | Deportivo Municipal | Europa League | 2 - 1 |
| 05.11.2028 | 20:00 | H | Olimpia | Champions League | 1 - 1 |
| 07.11.2028 | 20:00 | H | Deportivo Municipal | Europa League | 1 - 0 |
| 26.11.2028 | 20:00 | H | Sporting Cristal | Champions League | 0 - 0 |
| 28.11.2028 | 20:00 | A | Talleres | Europa League | 1 - 0 |
| 10.12.2028 | 20:00 | A | Flamengo | Champions League | - |
| 12.12.2028 | 20:00 | A | Sol de America | Europa League | - |