| Datum | Zeit | Spielort | Gegner | Wettbewerb | Ergebnis |
|---|---|---|---|---|---|
| 06.02.2027 | 00:00 | H | General Diaz | Primera Division | 1 - 1 |
| 13.02.2027 | 00:00 | A | Sportivo Trinidense | Primera Division | 0 - 1 |
| 27.02.2027 | 00:00 | A | Sol de America | Primera Division | 0 - 1 |
| 06.03.2027 | 00:00 | H | Guarani | Primera Division | 1 - 2 |
| 13.03.2027 | 00:00 | H | River Plate | Primera Division | 1 - 0 |
| 20.03.2027 | 00:00 | A | Nacional | Primera Division | 1 - 1 |
| 27.03.2027 | 00:00 | H | General Caballero | Primera Division | 2 - 0 |
| 03.04.2027 | 00:00 | A | 12 de Octubre | Primera Division | 3 - 1 |
| 10.04.2027 | 00:00 | H | Sportivo Luqueno | Primera Division | 1 - 2 |
| 17.04.2027 | 00:00 | A | Cerro Porteno | Primera Division | 1 - 1 |
| 24.04.2027 | 00:00 | A | General Diaz | Primera Division | 0 - 1 |
| 01.05.2027 | 00:00 | H | Sportivo Trinidense | Primera Division | 1 - 0 |
| 08.05.2027 | 00:00 | A | Libertad | Primera Division | 1 - 1 |
| 15.05.2027 | 00:00 | H | Sol de America | Primera Division | 1 - 1 |
| 22.05.2027 | 00:00 | A | Guarani | Primera Division | 0 - 1 |
| 29.05.2027 | 00:00 | A | River Plate | Primera Division | 0 - 0 |
| 12.06.2027 | 00:00 | A | General Caballero | Primera Division | 0 - 1 |
| 19.06.2027 | 00:00 | H | 12 de Octubre | Primera Division | 2 - 1 |
| 03.07.2027 | 00:00 | H | Cerro Porteno | Primera Division | 2 - 2 |
| 19.09.2027 | 20:00 | A | Racing Club | Europa League | 0 - 0 |
| 03.10.2027 | 20:00 | A | Cerro | Europa League | 0 - 0 |
| 24.10.2027 | 20:00 | H | Deportivo Cali | Europa League | - |
| 07.11.2027 | 20:00 | A | Deportivo Cali | Europa League | - |
| 28.11.2027 | 20:00 | H | Racing Club | Europa League | - |
| 12.12.2027 | 20:00 | H | Cerro | Europa League | - |