| # | Clube | J | V | D | D | SG | Pts |
|---|---|---|---|---|---|---|---|
| 1 | Columbus Crew | 10 | 7 | 3 | 0 | +10 | 24 |
| 2 | Atlanta United FC | 9 | 7 | 2 | 0 | +11 | 23 |
| 3 | Chicago Fire | 9 | 4 | 4 | 1 | +6 | 16 |
| 4 | Orlando City | 10 | 4 | 2 | 4 | -1 | 14 |
| 5 | Inter Miami CF | 10 | 2 | 7 | 1 | +8 | 13 |
| 6 | Charlotte Football Club | 9 | 4 | 1 | 4 | -1 | 13 |
| 7 | New York City | 10 | 3 | 3 | 4 | -1 | 12 |
| 8 | Toronto FC | 9 | 3 | 3 | 3 | -1 | 12 |
| 9 | New York Red Bulls | 10 | 3 | 3 | 4 | -3 | 12 |
| 10 | Nashville SC | 9 | 2 | 5 | 2 | +1 | 11 |
| 11 | New England Revolution | 9 | 1 | 6 | 2 | -2 | 9 |
| 12 | Philadelphia Union | 9 | 1 | 4 | 4 | -6 | 7 |
| 13 | CF Montreal | 9 | 1 | 4 | 4 | -9 | 7 |
| 14 | DC United | 9 | 1 | 3 | 5 | -4 | 6 |
| 15 | FC Cincinnati | 9 | 1 | 2 | 6 | -8 | 5 |
| # | Jogador | Jogos | Gls |
|---|---|---|---|
| 1 | Embolo Breel Atlanta United FC | 9 | 9 |
| 2 | Messi Lionel Inter Miami CF | 10 | 7 |
| 3 | Munteanu Louis DC United | 9 | 7 |
| 4 | Abou Ali Wessam Columbus Crew | 9 | 6 |
| 5 | Suárez Luis Inter Miami CF | 8 | 6 |
| 6 | Magno Talles New York City | 10 | 6 |
| 7 | Thiaré Jamal Columbus Crew | 6 | 4 |
| 8 | Qasem Ahmed Nashville SC | 9 | 4 |
| 9 | Griezmann Antoine Orlando City | 10 | 3 |
| 10 | Morgan Lewis Toronto FC | 8 | 3 |
| # | Jogador | Jogos | Ass |
|---|---|---|---|
| 1 | Tapia Gonzalo Columbus Crew | 10 | 7 |
| 2 | Almirón Miguel Atlanta United FC | 9 | 4 |
| 3 | Gutman Andrew Chicago Fire | 9 | 4 |
| 4 | Messi Lionel Inter Miami CF | 10 | 4 |
| 5 | Reguilón Sergio Inter Miami CF | 10 | 4 |
| 6 | Abou Ali Wessam Columbus Crew | 9 | 4 |
| 7 | Báez Elías Atlanta United FC | 9 | 4 |
| 8 | Magno Talles New York City | 10 | 3 |
| 9 | Paul Rodrigo De Inter Miami CF | 10 | 3 |
| 10 | Zaha Wilfried Charlotte Football Club | 8 | 3 |
| # | Jogador | Jogos | Not |
|---|---|---|---|
| 1 | Embolo Breel Atlanta United FC | 9 | 7.15 |
| 2 | Abou Ali Wessam Columbus Crew | 9 | 7.09 |
| 3 | Messi Lionel Inter Miami CF | 10 | 7.05 |
| 4 | Suárez Luis Inter Miami CF | 8 | 7.04 |
| 5 | Paul Rodrigo De Inter Miami CF | 10 | 7.01 |
| 6 | Munteanu Louis DC United | 9 | 7.00 |
| 7 | Magno Talles New York City | 10 | 7.00 |
| 8 | Galarza Matías Atlanta United FC | 9 | 6.96 |
| 9 | Ojeda Martín Orlando City | 9 | 6.91 |
| 10 | Galoppo Giuliano Atlanta United FC | 9 | 6.91 |